Combinatorial synthesis of galactosyl-1,3,5-triazines as novel nucleoside analogues.
نویسندگان
چکیده
Herein we report a parallel solid-phase synthesis of 1,3,5-triazine based nucleoside analogues by a three-step substitution, starting from 2,4,6-trichloro-1,3,5-triazine. A library of 80 galactosyl-1,3,5-triazine compounds was prepared in high purity without extensive reaction conditions or tedious purification, suggesting the generality of this method.
منابع مشابه
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 9 20 شماره
صفحات -
تاریخ انتشار 2011